AQUREA 20 MOISTURIZING CREAM

Research indicates that ceramide-containing emollients may improve barrier function and modulate microbial communities through restoration of stratum corneum lipids, hydration, and immune regulation. Studies suggest these effects may help relieve symptoms associated with sensitive skin conditions.

Authors not listed Skin Pharmacology and Physiology. 2026. PubMed →

Research suggests that ceramide NP-containing formulations, when combined with complementary ingredients, may support management of sensitive skin conditions. Evidence indicates a holistic skincare approach incorporating ceramide NP may be beneficial in clinical practice.

Authors not listed Journal of Cosmetic Dermatology. 2025. PubMed →

Molecular dynamics simulations indicate that ceramide NP-containing stratum corneum lipid membranes demonstrate significantly lower water permeability compared to ceramide NS-containing systems. Research suggests ceramide NP is associated with healthy, unimpaired skin barrier function.

Authors not listed Molecular Pharmaceutics. 2025. PubMed →

Studies indicate that ceramide NP-based creams retain ceramide in the stratum corneum for extended periods (up to 24 hours post-application) compared to aqueous-based creams. Research validates improved ceramide delivery and retention with handheld confocal Raman spectroscopy assessment.

Authors not listed Journal of Biophotonics. 2025. PubMed →

Research suggests that topical application of ceramide-containing moisturizers may improve barrier function by increasing stratum corneum ceramide levels. Studies indicate ceramide absorption into the stratum corneum may enhance overall ceramide profiles and reduce transepidermal water loss.

Authors not listed Journal of Cosmetic Dermatology. 2025. PubMed →

Research indicates that oral administration of lactic acid bacteria metabolites improved ceramide AP content in the stratum corneum and reduced transepidermal water loss in an atopic dermatitis-like murine model. Studies suggest the lipid fraction derived from bacterial metabolites may help support ceramide AP restoration and barrier function improvement. Evidence indicates these effects were associated with normalized stratum corneum water content and reduced epidermal thickness.

Study authors not specified in abstract Nutrients. 2018. PubMed →

Research using neutron diffraction indicates that ceramide AP in combination with ceramide NS, cholesterol, and lignoceric acid forms lamellar structures with repeat distances of 5.34-5.43 nm in stratum corneum model systems. Studies suggest these lipid mixtures display slightly tilted ceramide arrangements with overlapping C24 chains in the lamellar mid-plane. Evidence indicates water content and structure remain stable under varying humidity conditions.

Study authors not specified in abstract Chemistry and Physics of Lipids. 2018. PubMed →

Research indicates that the d-isomer (natural form) of ceramide AP promotes native-like lipid phase behavior when combined with other stratum corneum lipids, while the l-isomer shows crystalline-like characteristics. Studies suggest the d-ceramide AP configuration may be more appropriate for barrier restoration applications. Evidence indicates isomer-specific differences in lamellar organization may have implications for ceramide replacement therapies.

Study authors not specified in abstract Chemistry and Physics of Lipids. 2017. PubMed →

Research indicates that coarse-grain molecular dynamics models of ceramide AP have been developed and validated against atomistic simulations and experimental data. Studies suggest these computational models may help elucidate the structural role of ceramide AP in stratum corneum barrier organization. Evidence indicates these models can capture ceramide AP interactions with other major skin lipids and cholesterol at biologically relevant time and length scales.

Study authors not specified in abstract Journal of Molecular Modeling. 2020. PubMed →

Research indicates that ceramide AP-containing model lipid mixtures (CER[AP]/stearic acid/cholesterol) mimic intercellular lipid organization in the stratum corneum. Studies suggest synthetic surfactants alter the surface properties and rheological behavior of these ceramide AP-containing systems. Evidence indicates ceramide AP-containing lipid systems demonstrate distinct mechanical properties compared to phospholipid-cholesterol mixtures.

Study authors not specified in abstract Biochimica et Biophysica Acta. Biomembranes. 2019. PubMed →

Research indicates that sodium hyaluronate combined with amino acids (glycine, alanine, proline) may enhance moisturizing performance compared to mono-component formulations. Studies suggest this combination strategy may reduce dosing frequency and improve hydration efficacy in skin rejuvenation applications.

Not specified in abstract Journal of Cosmetic Dermatology. 2026. PubMed →

Research suggests that hyaluronic acid derivatives demonstrate high structural stability across gastrointestinal stages and may exert superior antioxidant and anti-inflammatory activity. Studies indicate efficient intestinal barrier penetration without increased enzymatic degradation, with potential upregulation of CD44 receptor expression in keratinocytes.

Not specified in abstract Foods (Basel, Switzerland). 2026. PubMed →

Studies indicate sodium hyaluronate can be successfully formulated in hydrogel systems with complementary ingredients such as xanthan gum, demonstrating adequate physical and microbiological stability over extended storage periods. Research suggests these formulations maintain tunable rheological properties suitable for dermal administration.

Not specified in abstract Gels (Basel, Switzerland). 2026. PubMed →