Physiogel Calming Relief A.I. Cream

Research indicates that ceramide-containing emollients may improve barrier function and modulate microbial communities through restoration of stratum corneum lipids, hydration, and immune regulation. Studies suggest these effects may help relieve symptoms associated with sensitive skin conditions.

Authors not listed Skin Pharmacology and Physiology. 2026. PubMed →

Research suggests that ceramide NP-containing formulations, when combined with complementary ingredients, may support management of sensitive skin conditions. Evidence indicates a holistic skincare approach incorporating ceramide NP may be beneficial in clinical practice.

Authors not listed Journal of Cosmetic Dermatology. 2025. PubMed →

Molecular dynamics simulations indicate that ceramide NP-containing stratum corneum lipid membranes demonstrate significantly lower water permeability compared to ceramide NS-containing systems. Research suggests ceramide NP is associated with healthy, unimpaired skin barrier function.

Authors not listed Molecular Pharmaceutics. 2025. PubMed →

Studies indicate that ceramide NP-based creams retain ceramide in the stratum corneum for extended periods (up to 24 hours post-application) compared to aqueous-based creams. Research validates improved ceramide delivery and retention with handheld confocal Raman spectroscopy assessment.

Authors not listed Journal of Biophotonics. 2025. PubMed →

Research suggests that topical application of ceramide-containing moisturizers may improve barrier function by increasing stratum corneum ceramide levels. Studies indicate ceramide absorption into the stratum corneum may enhance overall ceramide profiles and reduce transepidermal water loss.

Authors not listed Journal of Cosmetic Dermatology. 2025. PubMed →