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§ 01 · Pigmentation · Kochi

Melasma treatment in Kochi,
on the IJDVL protocol.

Low-fluence Q-switched Nd:YAG laser toning, triple combination cream priming, oral tranexamic acid, iron-oxide SPF 50, and a structured 12–18 month maintenance plan. Calibrated for Fitzpatrick IV–VI skin by board-certified dermatologists.

4.8★ 1,450 reviews
MD DVL Board-certified
US-FDA Approved lasers
IJDVL Published protocol
100 m from Pulinchodu Metro · 15 min from Lulu Mall · 25 min from Kochi city centre
§ 02 · Quick Answer

What melasma actually responds to.

Melasma treatment at DermaVue Kochi combines triple-combination topical cream (hydroquinone + tretinoin + fluocinolone) with low-fluence Q-switched Nd:YAG laser at 1064 nm (0.5-1 J/cm², 10 mm spot, multiple passes, 2-week intervals × 6-8 sessions), the IJDVL-published protocol calibrated for Fitzpatrick IV-VI Indian skin. Adjuncts: oral tranexamic acid 250 mg twice daily, daily SPF 50 with iron oxide. Maintenance therapy is mandatory; recurrence without maintenance reaches 58.8% at one year. Consultation ₹300.

§ 03 · The Protocol

Five phases. Same hands. From diagnosis to maintenance.

Every melasma case at DermaVue starts at dermoscopy and Wood's lamp, not at the laser. The depth of pigment determines everything that follows.

01

Dermoscopy + Wood's lamp

Classify epidermal vs dermal vs mixed melasma, this determines laser response and the realistic clearance timeline.

02

Priming phase

Triple combination cream (TCC) once nightly for 4-8 weeks. Mandatory daily SPF 50 with iron oxide for visible-light protection.

03

Laser toning

1064 nm Q-switched Nd:YAG at 0.5-1 J/cm², 10 mm spot, multiple passes, 2-week intervals × 6-8 sessions.

04

Oral adjunct (selected patients)

Tranexamic acid 250 mg twice daily × 8-12 weeks after VTE screen, meaningful added MASI reduction in trial cohorts.

05

Maintenance

Reduced-frequency topicals + monthly/quarterly laser top-ups for 12-18 months. Recurrence without maintenance reaches 58.8% at one year.

Swipe →
§ 04 · Why Kochi Skin Is Different

Kochi sits at UV Index 11 for ten months of the year.

Classified "Extreme" by WHO — unprotected skin burns in under fifteen minutes. On Fitzpatrick IV–VI skin this is the single largest driver of melasma in South Asia. KSDMA issued an orange UV alert in April 2026.

  • 80.5%of South-India male melasma cases trace to occupational sun exposure (IMSEAR / WHO-indexed)
  • 21–30 yrspeak age of female melasma in Kerala (JCDR 2014)
  • 3.14 : 1female-to-male ratio of melasma cases (JPAD)
Weather2Travel Cochin · KSDMA April 2026 · IMSEAR / WHO
UV INDEX — EXTREME
11
months of the year
0
3 6 8 11
§ 05 · Clinical Summary

The published protocol, in plain English.

Melasma is the predominant pigmentary disorder in South Asian dermatology practice, driven by genetic predisposition, female sex hormones, and UV/visible-light exposure. The Indian Journal of Dermatology, Venereology and Leprology (IJDVL) has published the optimal laser-toning protocol for Fitzpatrick IV-VI: 1064 nm Q-switched Nd:YAG at low fluence 0.5-1 J/cm² with a 10 mm spot size and multiple passes, repeated every 2 weeks for 6-8 sessions. This differs critically from the Western high-fluence protocols, which carry a high risk of paradoxical mottled hypopigmentation in darker skin.

The combined approach, triple combination cream (TCC) as priming, followed by low-fluence Q-switched Nd:YAG laser, delivers MASI (Melasma Area Severity Index) reductions of 53% (laser combined) versus 50% (TCC alone), per the comparative IJDVL study. TCC's standard formulation is hydroquinone 2-4% + tretinoin 0.05% + fluocinolone 0.01% (Tri-Luma / Melalite Forte combinations) applied once nightly under dermatologist monitoring.

Adjunctive oral tranexamic acid at 250 mg twice daily for 8-12 weeks has emerged as a meaningful addition, reducing serum-melanin precursor levels and offering meaningful MASI reduction in trial cohorts, with VTE risk screening before initiation. The non-negotiable: maintenance therapy + daily broad-spectrum SPF 50 (with iron oxide for visible-light protection). Recurrence without maintenance reaches 58.8% at one year per a longitudinal IJDVL study, with some studies reporting up to 81%. Maintenance combines reduced-frequency topical TCC or alternating-day topicals + monthly/quarterly laser-toning top-ups.

§ 06 · Compare

What changes when a board-certified dermatologist runs the protocol.

RECOMMENDED DermaVue Kochi (MD DVL dermatologist)
ALTERNATIVE Generic clinic / parlour
Diagnosis (dermal vs epidermal vs mixed)
Wood's lamp + dermoscopy
Often not done
Laser parameters
Low fluence 0.5-1 J/cm², 10 mm spot, multiple passes (IJDVL-published, safe for Fitzpatrick IV-VI)
High fluence Western protocols → paradoxical hypopigmentation risk
Topical regimen
Triple combination cream (TCC) with periodic 2-month breaks to avoid steroid atrophy
Open-ended unsupervised hydroquinone
Adjuncts
Oral tranexamic acid with VTE screening, niacinamide, mandatory iron-oxide SPF 50
None or generic sunscreen only
Maintenance protocol
Structured 12-18 month maintenance after clearance
Not offered; recurrence near-universal
§ 07 · Transparent pricing

Each line item. No package inflation.

Pricing starts from ₹300 consultation. Final quote after your diagnostic visit.

Dermatology consultation From ₹300
Triple combination cream (3-month course) From ₹1,800–3,600
Q-switched Nd:YAG laser toning From ₹4,500–15,000 / session · course of 6-8
Oral tranexamic acid (3-month course) From ₹600–1,800
Iron-oxide SPF 50 sunscreen (3 months) From ₹900–1,800
All pricing starts from the amounts shown. Final treatment plan and cost confirmed after consultation. ₹300 covers the full diagnostic visit.
§ 08 · What's in the room

Eight modalities, sequenced per patient.

01

Wood's Lamp + Dermoscopy Diagnosis

classifies epidermal / dermal / mixed melasma

02

Triple Combination Cream Priming

hydroquinone 2-4% + tretinoin 0.05% + fluocinolone 0.01%

03

Low-Fluence Q-Switched Nd:YAG Laser Toning

IJDVL parameters for Fitzpatrick IV-VI

04

Oral Tranexamic Acid Therapy

250 mg twice daily × 8-12 weeks after VTE screen

05

Iron-Oxide SPF 50 Photoprotection

visible-light blocker, mandatory daily

06

Chemical Peel Combination

glycolic 70% for select patients

07

Maintenance Programme

structured 12-18 month plan to prevent recurrence

08

Niacinamide + Cysteamine Topical Adjuncts

for hydroquinone-intolerant patients

§ 08b · Watch the protocol

Our dermatologists explain the protocol on camera.

Board-certified dermatologists walk through the clinical approach — watch before your first visit.

Melasma Treatment Protocol · Dr. Minu Liz Mathew
Melasma Treatment Protocol · Dr. Minu Liz Mathew
CLIP 01 Melasma Treatment Protocol · Dr. Minu Liz Mathew Dr. Minu Liz Mathew explains the IJDVL-published Q-switched Nd:YAG protocol for melasma in Indian skin.
Triple Cream + Laser Combination for Melasma
Triple Cream + Laser Combination for Melasma
CLIP 02 Triple Cream + Laser Combination for Melasma Triple combination cream priming followed by low-fluence Q-switched Nd:YAG laser.
§ 09 · Patient case

I came to DermaVue with 4 years of failed melasma treatments behind me. Dr. Minu started the IJDVL protocol, triple cream priming, then low-fluence laser sessions every 2 weeks. By session 5 my pigmentation was 60% lighter. The maintenance plan is what keeps it from coming back. Twelve months in, my skin tone is even and stable.

Lakshmi Pillai Kakkanad · Kochi · DermaVue Kochi patient
§ 10 · Your dermatologists

Five names on every consultation note.

One physician owns your file from intake through the 12–18 month maintenance phase. Continuity of care isn't a tagline here, it's the default.

  1. Dr. Minu Liz Mathew, MBBS, MD DVL, Chief Dermatologist at DermaVue Kochi
    01

    Dr. Minu Liz Mathew, MBBS, MD DVL

    Chief Dermatologist

    Dermatology, Cosmetic Dermatology, Lasers & Aesthetic Medicine

    • IADVL
    • ACSI
    • IMA
    • 15+ years
  2. Dr. Navya K G, MBBS, MD DVL, Consultant Dermatologist at DermaVue Kochi
    02

    Dr. Navya K G, MBBS, MD DVL

    Consultant Dermatologist

    Medical Dermatology, Cosmetic Procedures

    • IADVL
    • 9 yrs experience
  3. Dr. Arjun K, MBBS, DDVL, Consultant Dermatologist at DermaVue Kochi
    03

    Dr. Arjun K, MBBS, DDVL

    Consultant Dermatologist

    Venereology, Medical Dermatology

    • IADVL
    • 8 yrs experience
  4. Dr. Reshma J Neerackal, MBBS, MD DVL, Consultant Dermatologist at DermaVue Kochi
    04

    Dr. Reshma J Neerackal, MBBS, MD DVL

    Consultant Dermatologist

    Cosmetic Dermatology, Aesthetic Procedures

    • IADVL
    • 12 yrs experience
  5. Dr. Johna PS, MDS, FUE Trained, Hair Transplant Surgeon at DermaVue Kochi
    05

    Dr. Johna PS, MDS, FUE Trained

    Hair Transplant Surgeon

    FUE Hair Transplant, Beard & Eyebrow Restoration

    • APSI
    • 100+ procedures

Direct line to the team WhatsApp +91 90720 07733 →

§ 11 · Frequently asked

The questions every melasma patient asks. Honestly answered.

Why does my melasma keep coming back?

Recurrence after melasma treatment reaches 58.8% at one year per a longitudinal IJDVL study (some studies report up to 81%), without structured maintenance therapy. The recurrence drivers are continued UV/visible-light exposure (especially morning commute and screen time), hormonal triggers (combined oral contraceptives, pregnancy), and discontinuation of topical therapy. DermaVue's structured maintenance combines reduced-frequency topicals + monthly/quarterly laser top-ups + mandatory iron-oxide SPF 50 for 12-18 months after initial clearance.

Is hydroquinone safe long-term?

Hydroquinone is safe and effective when used in 4-month courses with 2-month breaks under dermatologist monitoring. Open-ended unsupervised use (common with parlour-prescribed creams) carries a small but documented risk of exogenous ochronosis, paradoxical darkening that's harder to reverse than the original melasma. DermaVue uses the triple combination cream (hydroquinone + tretinoin + fluocinolone) on a structured pulse protocol with dermatologist follow-up, then rotates to alternatives (cysteamine, niacinamide, kojic acid, azelaic acid) during break periods.

What is the difference between melasma and post-inflammatory hyperpigmentation?

Melasma is a chronic hormone-and-UV-driven pigmentary disorder with characteristic symmetric facial patterns (malar, central facial, mandibular). Post-inflammatory hyperpigmentation (PIH) is reactive, it follows a specific inflammatory event (acne lesion, eczema flare, contact dermatitis, laser burn). Dermoscopy and Wood's lamp distinguish them: melasma typically shows a reticular pigment network with hormone-pattern distribution; PIH shows localised pigment at the previous inflammatory site. Treatment differs: melasma needs the full TCC + laser + maintenance protocol; PIH often resolves with azelaic acid + SPF + time.

Does Q-switched laser work for melasma in dark skin?

Yes, but ONLY at low fluence (0.5-1 J/cm²) with a 10 mm spot size and multiple passes, repeated every 2 weeks. The high-fluence Western protocols cause paradoxical mottled hypopigmentation in Fitzpatrick IV-VI skin and should not be used. The IJDVL low-fluence protocol DermaVue follows has been published with consistent safety data for South Asian skin, achieving 53% MASI reduction in trial cohorts when combined with triple combination cream priming.

Can I take oral tranexamic acid for melasma?

Oral tranexamic acid 250 mg twice daily for 8-12 weeks reduces serum melanin precursors and produces meaningful MASI reduction in trial cohorts. DermaVue prescribes it as an adjunct after a venous thromboembolism (VTE) risk screen, patients with personal or family history of clots, current OCP use, or smoking should not take it. Most patients tolerate it well; transient GI symptoms are the commonest minor side effect.

How many laser sessions will I need for melasma?

The standard IJDVL protocol is 6-8 sessions of low-fluence Q-switched Nd:YAG at 2-week intervals, about 3-4 months of active treatment. Maintenance top-ups continue monthly to quarterly for 12-18 months after initial clearance. Dermal-pattern melasma (versus epidermal) responds more slowly and may need additional sessions. Wood's lamp at the first consultation classifies the type and predicts the realistic timeline.

Can melasma go away completely?

Clinical clearance is achievable for the majority of epidermal-pattern melasma patients with the full IJDVL protocol (TCC priming + low-fluence Q-switched laser + tranexamic acid + photoprotection). What's not achievable is permanent cure, the genetic and hormonal drivers remain, so without structured maintenance, recurrence at 12 months is common. DermaVue's framing is: clearance is achievable, maintenance is mandatory, the result is stable manageable skin not permanent cure.

What sunscreen do you recommend for melasma?

Iron-oxide-tinted SPF 50 broad-spectrum sunscreen, daily, reapplied every 2-3 hours of sun exposure. The iron oxide is critical, UV-only sunscreens leave melasma vulnerable to visible-light-driven pigment activation (which screen time and indoor lighting also contribute to). DermaVue recommends specific brands at the consultation; budget reasonable choices are widely available.

Is melasma related to pregnancy?

Yes, pregnancy melasma (chloasma) is one of the commonest variants, affecting 50-70% of pregnant women in Indian cohorts. It typically appears in the second trimester and may persist post-partum. Treatment during pregnancy is limited to SPF 50 + iron oxide + topical azelaic acid (the only pigment-lightener safe in pregnancy). The full protocol, TCC, laser, tranexamic acid, starts post-partum and post-lactation.

What is the cost of melasma treatment in Kochi?

₹300 consultation. Triple combination cream is ₹1,800-3,600 for a 3-month course. Q-switched Nd:YAG laser toning is ₹4,500-15,000 per session (a 6-8 session course is ₹27,000-1,20,000 total). Oral tranexamic acid is ₹600-1,800 for a 3-month course. Iron-oxide SPF 50 sunscreen is ₹900-1,800 for 3 months. Maintenance after initial clearance is structured at lower frequency to keep recurring costs predictable.

§ 12b · Read deeper

Melasma is one expression of a broader condition family.

Many patients arrive at our Kochi clinic having read about melasma in isolation, when the underlying mechanism is shared with other forms of hyperpigmentation. The condition hubs below pull the published evidence together — read alongside this page for the full picture.

§ 13 · Find us

15 min from Lulu Mall. 100 m from Pulinchodu Metro.

Address
Metro Rail Pillar No. 57, Tamarind Rajadhani Building, Near Pulinchodu, NH-47, Aluva, Kerala 683101
Hours
Mon–Sat 9 AM–6:30 PM · Sun 11 AM–5 PM
KochiErnakulamAluvaEdappallyKakkanadKaloorKalamasseryThrikkakara
§ 15 · Start today

Book the dermoscopy + Wood's lamp visit.
The rest of the protocol starts after that.

₹300 consultation · same-day slots available · Aluva clinic open Mon–Sat 9 AM – 7 PM, Sun 10 AM – 6 PM.

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