PRP (Platelet-Rich Plasma) and GFC (Growth Factor Concentrate) are the two regenerative injection modalities for androgenetic alopecia at DermaVue Kochi, both work by isolating growth factors from the patient's own blood and injecting them into the affected scalp zone to stimulate dormant follicles back into anagen phase.
**PRP** is the older, more-studied therapy. The IADVL 2024 consensus specifies a minimum platelet concentration of 1×10⁶ platelets/µL (4-7× the patient's baseline) for therapeutic efficacy, concentrations below this are sub-clinical. The standard protocol is monthly injection × 3-5 sessions, followed by maintenance every 4-6 months. Indian Dermatology Online Journal (IDOJ) 2021 reported PRP as effective for Norwood II-V AGA, with response visible at month 3 and peak at month 6.
**GFC** is the newer, more concentrated platelet-derivative therapy. By removing the red and white blood cells from the PRP preparation, GFC delivers higher purified growth-factor concentration with less inflammatory burden (less pain, faster recovery). A 2024 comparative study published in the Journal of Dermatological Case Reports reported GFC yielding 28.6 hairs/cm² versus PRP's 19.2, a 49% superior density gain. The same study reported 83% positive response in the GFC cohort.
At DermaVue Kochi, PRP/GFC is rarely used as monotherapy. The standard approach combines injection therapy with topical minoxidil 5% daily and, in male patients with confirmed AGA and no contraindications, oral finasteride 1 mg/day. Female patients with non-androgen-driven hair loss receive a 6-blood workup (ferritin, vitamin D, TSH, free T3/T4, ANA, fasting insulin) before injection therapy starts, many cases are nutritional or thyroid-related, not AGA, and injecting growth factors into a non-AGA scalp wastes patient money.
Session experience: 30-45 minutes total. Numbing cream applied 20 minutes pre-procedure; mild pain 2-3/10 during; no downtime. Return to work same day; no exercise / swimming / pool for 24 hours post-session.